Goat Secondary Antibodies
Cayman Chemical Teneligliptin (hydrobromide hydrate), Purity: ≥98%, CAS: 1572583-29-9, 50 mg
A DPP-4 inhibitor (IC50s = 0.37 and 0.29 nM for the human and rat enzymes, respectively); selective for DPP-4 over DPP-8 and DPP-9 (IC50s = 260 and 540 nM, respectively, for the human enzymes); inhibits increases in plasma glucose levels in an oral glucose tolerance test in Zucker fatty rats at 0.03-1 mg/kg; reduces body weight, inhibits hepatic steatosis, and decreases plasma insulin levels in a mouse model of high-fat diet-induced obesity at 30 and 60 mg/kg; scavenges hydroxyl radicals in a cell-free assay (IC50 = 0.315 mM); decreases urinary levels of 8-OHdG in a DPP-4-deficient rat model of STZ-induced diabetes at 10 mg/kg per day
Cayman Chemical (Des-Arg9)-Bradykinin, Purity: ≥98%, CAS: 15958-92-6, 50 mg
An active metabolite of bradykinin and a peptide agonist of the bradykinin B1 receptor; binds to bradykinin B1 and B2 receptors (IC50 = 8.1 µM in CHO cells expressing the human receptor); induces relaxation of precontracted isolated endothelium-denuded dog renal artery strips (pD2 = 8.6); decreases blood pressure in LPS-treated rabbits in a dose-dependent manner
Cayman Chemical Flumethasone, Purity: ≥98%, CAS: 2135-17-3, 500 mg
An agonist of glucocorticoid and mineralocorticoid receptors (EC50s = 0.26 and 0.494 nM, respectively, in CV-1 cells expressing human receptors); inhibits the growth of UM-UC-3, TCC-SUP, and 5637 urothelial carcinoma cell lines (100 nM); decreases TNF production ex vivo in blood cells collected by BAL from calves with experimentally-induced local lung inflammation (5 mg per animal); impairs cell cycle re-entry of cardiac cells seven days post cryo-injury to the heart and impairs cardiac regeneration in vivo in zebrafish (5 μM)
Cayman Chemical C12 NBD GlobotrIaosylcRamID
A fluorescently tagged sphingolipid; a derivative of globotriaosylceramide that is tagged with a fluorescent C12 NBD; accumulates in HUVECs treated with DGJ in a concentration-dependent manner
Cayman Chemical n-Nonyl-β-D-glucopyranoside, Purity: ≥95%, CAS: 69984-73-2, 1 g
An anionic chiral surfactant; commonly used for the solubilization and crystallization of biological membrane proteins; has been used in the separation of drug enantiomers by micellar electrokinetic chromatography
Cayman Chemical 3-Butylidenephthalide, Purity: ≥98%, CAS: 551-08-6, 100 g
A plant metabolite with diverse biological activities; induces apoptosis and inhibits migration and EMT in 5637, BFTC-905, T24, and TCCSUP cells at 60 µg/ml; reduces tumor volume in a BFTC-905 mouse xenograft model at 100 and 200 mg/kg; increases life span and reduces spinal motor neuron loss in an SOD1G93A mouse model of ALS at 400 mg/kg; reduces polyQ accumulation and cerebral atrophy, as well as improves motor coordination in a mouse model of SCA3
Cayman Chemical Prostaglandin E2 Express AChE Tracer, 500 dtn
Prostaglandin E2 Express AChE Tracer, 500 dtn
Cayman Chemical Dihydrostreptomycin (sulfate), Purity: ≥95%, CAS: 5490-27-7, 250 g
An aminoglycoside antibiotic and a derivative of streptomycin; active against B. subtilis, K. pneumoniae, S. marcescens, S. aureus, P. aeruginosa, and M. tuberculosis (MICs = 0.07, 0.08, 0.09, 0.06, 0.8, and 5.7 µg/ml, respectively); interferes with bacterial protein synthesis by binding the 30S ribosomal subunit; enhances phagocytosis and intracellular killing of E. coli by isolated mouse peritoneal macrophages; improves survival in a mouse model of S. aureus infection
Cayman Chemical N-methyl para-methyl Phenyl fentanyl (hydrochloride), Purity: ≥98%, CAS: 2710510-11-3, 1 mg
An analytical reference standard that is structurally similar to known opioids; intended for research and forensic applications
Cayman Chemical Dihydrostreptomycin (sulfate), Purity: ≥95%, CAS: 5490-27-7, 500 g
An aminoglycoside antibiotic and a derivative of streptomycin; active against B. subtilis, K. pneumoniae, S. marcescens, S. aureus, P. aeruginosa, and M. tuberculosis (MICs = 0.07, 0.08, 0.09, 0.06, 0.8, and 5.7 µg/ml, respectively); interferes with bacterial protein synthesis by binding the 30S ribosomal subunit; enhances phagocytosis and intracellular killing of E. coli by isolated mouse peritoneal macrophages; improves survival in a mouse model of S. aureus infection
ABclonal Technology PerCP/Cyanine5.5 anti- CD93
Predicted to enable complement component C1q complex binding activity Predicted to be involved in cell-cell adhesion Predicted to act upstream of or within cell adhesion Located in cell surface cytoplasmic vesicle and plasma membrane Is expressed in blood vessel Orthologous to human CD93 (CD93 molecule)